The best evidence that ALA can protect the heart comes from the Lyon Diet Heart Study, a randomized clinical trial in Europe. It tested the effects of an ALA-enriched Mediterranean diet in 605 patients with coronary artery disease. Over a four-year period, the high-ALA diet produced a 72% reduction in heart attacks and cardiac deaths and a 56% lower risk of dying from any cause (including cancer). The Mediterranean diet differed from the standard Western diet in many respects, but because it contained a special canola oil margarine, the greatest difference was in its ALA content, which was nearly eight times higher in the protective diet.
Getting enough water also is important. Many experts recommend at least eight 8-ounce glasses of water daily—more if you exercise frequently or are exposed to extremes of heat and cold. The 2010 Dietary Guidelines for Americans emphasize drinking more water and other calorie-free beverages, along with fat-free or low-fat milk and 100 percent fruit juices, instead of calorie-packed regular sodas.